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Publishing Very Large Documents on Windows
When publishing very large documents to PDF on Windows, the publishing process may fail with an Out of virtual memory space error message. This situation can occur when the publishing process encounters a Windows 2GB memory addressing limitation. You can update your Windows boot.ini file to address 3GB of memory using the instructions provided on Microsoft's web site at http://www.microsoft.com/whdc/system/platform/server/PAE/PAEmem.mspx
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Ensure that you make the change exactly as described in the Microsoft documentation. Incorrectly modifying system files can leave your workstation in an unstable state.